Alzheimer’s disease is difficult to detect. Until one starts showing signs at an old age, no one can know if they are suffering from it.
Alzheimer is a disease associated with memory loss. Most elderly people are known to be affected with it with no cure. But how does it all start? How long will it take to find a cure? Scientists are still working on it!
As the number of Alzheimer patients increase, scientists are working hard to deal with the situation. They have been working hard to find a way to catch the disease before it progresses.
And yes, a breakthrough has been achieved after years of hard work, research and dedication. Scientists have now found a way to catch the diseases before it shows symptoms.
They have introduced a blood test that monitors levels of proteins in people, with a success rate of 89% to 98 %. Samples from 1,400 people from Columbia, Arizona and Sweden for collected for the research. The samples were taken from people with no memory impairment, slight memory loss, Alzheimer and other neurological diseases.
According to Dr. Oskar Hansson, the research lead found p-tau217 in blood samples which can detect Alzheimer accurately.
According to Dr. Hansson, ‘This test, once verified and confirmed, opens the possibility of early diagnosis of Alzheimer’s before the dementia stage. It is very important for clinical trials evaluating novel therapies that might stop or slow down the disease process.’
The US based researchers found that before the symptoms of Alzheimer first appear, the p-tau217 starts accumulating in the cerebrospinal fluid in brain and spine. This disturbs the neurological pattern of the brain, thus leading to onset of Alzheimer and then dementia.
The Onset of the Disease
The scientists at Washington University School of Medicine in St Louis, Missouri, created a mass spectrometry based method for study. It was used to measure the amount of p-tau217 and other fragments of it in 4ml of blood.
According to the study, healthy volunteers with no disease had low levels of p-tau217. While for those with elevated amyloid plaques, the levels were shockingly high. Amyloid plaque is another protein commonly found in the brains of Alzheimer’s patients.
Another researcher, Dr Randall Bateman said: ‘Our findings support the idea that tau isoforms in the blood are potentially useful for detecting and diagnosing Alzheimer’s disease pathology.’
The scientists are working day and night to find a way to detect Alzheimer before its onset. Because once the symptoms starts showing, the disease progress quickly to a level where it becomes un-treatable.